Point Nemo is the most remote location on Earth
48°52.6′S 123°23.6′W are the coordinates of a place in the Pacific Ocean that is farthest from any landmass on Earth. The nearest lands are Ducie Island, Motu Nui (part of the Easter Islands) and Maher Island (Antarctica), each sepearated by 2,688 km (1,670 mi) of endless ocean to point Nemo. This means the nearest humans are often astronauts. The International Space Station orbits the Earth at a maximum of 258 miles (416km).
Speaking of astronauts, point Nemo is also known as a "spacecraft cemetery" because hundreds of decommissioned satellites, space stations, and other spacecraft have been crashed here into the ocean to lessen the risk of hitting any inhabited locations. The Russian space station MIR is one of them.
Even the fish don't like to live at this remote location. Point Nemo's location within the South Pacific Gyre blocks nutrients from reaching the area, and being so far from land it gets little nutrient run-off from coastal waters.